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Fiscal Wizard · Single-issue tearsheet

SPRO / Jun 21, 2026 Run #7298

SPRO

Spero Therapeutics, Inc.

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, manufacture, and commercialize tebipenem pivoxil and tebipenem HBr; and Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries. Spero Therapeutics, Inc. was incorporated in 2013 and is headquartered in Cambridge, Massachusetts.

Composite verdict

D 36.5 / 100
Bearish setup · Trend Following 17 drivers · 5 gates blocking
  • Rate of Change
  • Elder Force Index
  • Parabolic SAR Flip
Consider long put target Δ ~0.70 · ~35 DTE Bearish setup, Grade A → ITM put target

Industry rank 129th of 598 in Biotechnology

rescore-sweep
Technical synthesisRegime: volatile range
Bull 0%Evidence: High · 19 signals100% Bear
Momentum Bearish 3Mean-reversion Neutral 50

No notable composite patterns — the signals don't cluster into a named setup right now.

Where value comes from
Asset value $1.02Earnings power value $1.82Price $2.28

Priced above its no-growth earnings power value ($1.82/share) — you're paying for growth and franchise expansion, not just current earnings.

Fundamentals Strong

72.9 / 100

Score-bearing fundamentals shown here exclude gate-only risk checks. · 35 metrics shown.

Strongest
Weakest
EPS Growth (YoY) 100
OCF to Net Income 0
Revenue Growth (YoY) 100
Free Cash Flow Yield 0
Asset Turnover 100
Cash Conversion 0

Technicals Bearish

0.0 / 100

Bearish setup leads (Rate of Change, Elder Force Index, Parabolic SAR Flip); bulls gated by guards. · 43 signals shown.

Strongest
Weakest
Rate of Change 5
Elder Force Index 8
Parabolic SAR Flip 9

Risk Gates

5 blocking 5 caution

5 guards active, 21 signals gated.

Altman Z-Score Blocking

Bottom-band Altman Z blocks bullish signals — distress risk.

ADX Trend Weakness Blocking

Weak trend strength blocks trend-following signals in either direction.

MA Crossover Blocking

Blocks counter-regime signals only when the MA crossover agrees with the long-term regime.

Realized Volatility Regime Blocking

High-vol regime mutes mean-reversion signals; low-vol regime mutes breakout signals.

Breakdown

Look under the hood

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Every chip in either subscore card drills into the metrics or signals that fed it — including the formula, the threshold band, and what the current reading means for SPRO.