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Fiscal Wizard · Single-issue tearsheet

MLYS / Jun 22, 2026 Run #7637

MLYS

Mineralys Therapeutics, Inc.

Mineralys Therapeutics, Inc., a biopharmaceutical company, develops medicines to target diseases driven by dysregulated aldosterone in the United States. It is developing lorundrostat, a proprietary, orally administered, highly selective aldosterone synthase inhibitor for the treatment of cardiorenal conditions affected by dysregulated aldosterone, such as hypertension, chronic kidney disease, and obstructive sleep apnea. The company was formerly known as Catalys SC1, Inc. and changed its name to Mineralys Therapeutics, Inc. in May 2020. Mineralys Therapeutics, Inc. was incorporated in 2019 and is headquartered in Radnor, Pennsylvania.

Composite verdict

F 27.2 / 100
Bearish setup · Trend Following 16 drivers · 4 gates blocking
  • Chaikin Money Flow
  • Stochastic RSI
  • Vortex Signal
Consider long put target Δ ~0.70 · ~35 DTE Bearish setup, Grade A → ITM put target

Industry rank 192nd of 598 in Biotechnology

rescore-sweep
Technical synthesisRegime: range
Bull 0%Evidence: High · 20 signals100% Bear
Momentum Bearish 6Mean-reversion Neutral 46

No notable composite patterns — the signals don't cluster into a named setup right now.

Where value comes fromMargin of safety -91%

Earnings power doesn't cover the capital structure (high debt) — the EPV decomposition isn't meaningful for this name.

Fundamentals Mixed

54.4 / 100

Score-bearing fundamentals shown here exclude gate-only risk checks. · 35 metrics shown.

Strongest
Weakest
EPS Growth (YoY) 100
Margin of Safety 0
Greenblatt ROC 76
Free Cash Flow Yield 0
Return on Capital Employed 76
Return on Equity 25

Technicals Bearish

0.0 / 100

Bearish setup leads (Chaikin Money Flow, Stochastic RSI, Vortex Signal); bulls gated by guards. · 43 signals shown.

Strongest
Weakest
Chaikin Money Flow 4
Stochastic RSI 11
Coppock Curve 13

Risk Gates

4 blocking 5 caution

4 guards active, 20 signals gated.

Piotroski F-Score Blocking

Bottom-band Piotroski F blocks bullish signals — fundamental-quality risk.

MA Crossover Blocking

Blocks counter-regime signals only when the MA crossover agrees with the long-term regime.

Realized Volatility Regime Blocking

High-vol regime mutes mean-reversion signals; low-vol regime mutes breakout signals.

Regime Filter Blocking

Blocks signals that oppose the long-term moving-average regime.

Breakdown

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Every chip in either subscore card drills into the metrics or signals that fed it — including the formula, the threshold band, and what the current reading means for MLYS.